Amyloid-β Increases Metallo- and Cysteine Protease Activities in Human Macrophages
نویسندگان
چکیده
منابع مشابه
Amyloid-β increases metallo- and cysteine protease activities in human macrophages.
BACKGROUND/AIMS Amyloid-β (Aβ) plays a crucial role in the onset and progression of atherosclerosis. Macrophages are a source of matrix metalloproteinases (MMPs), cysteine proteases and transforming growth factor (TGF)-β1 in the vascular wall. The aims of this study were to analyze the capacity of Aβ peptide (1-40) (Aβ40), Aβ peptide (1-42) (Aβ42) and fibrillar Aβ42 (fAβ42) to modulate the expr...
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ژورنال
عنوان ژورنال: Journal of Vascular Research
سال: 2013
ISSN: 1018-1172,1423-0135
DOI: 10.1159/000356334